Combinatorial approach to the discovery of chiral catalysts for asymmetric reactions*
نویسنده
چکیده
The powerfulness of a combinatorial approach in the discovery of novel chiral catalyst systems, particularly for the development of highly efficient, enantioselective, and practical catalysts for asymmetric reactions, was demonstrated by screening modular chiral catalyst libraries created by the strategy of two-component ligand modification of metal ions on the basis of molecular recognition and assembly.
منابع مشابه
Development of homogeneous and heterogeneous asymmetric catalysts for practical enantioselective reactions*
Two strategies for the development of practical asymmetric catalysis have been discussed in this article. The first part of this article focuses on the design and screening of highly efficient and enantioselective chiral catalysts for asymmetric hydrogenation reactions employing combinatorial approach. The second part presents a conceptually new strategy (i.e., “self-supporting” approach) for t...
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